This is disappointing, I thought more people would speak up but I guess not.
I cannot take you, but I'll give you some experiences of my own and single women.
First and foremost, going to Bliss Out is the safest bet since you'll likely encounter some people you can communicate with. You can certainly go as a single female and if you're moderately attractive and outgoing, you'll have plenty of attention from the men and/or couples that may be there. Of course, it depends on the night... but it's possible that you may go on a night when it's not very busy. If you stick to Thur, Fri, Sat evenings, before last train, you should see a fair amount of activity.
Once inside, it's fairly straight forward as far as interacting with people in the bar. Just keep in mind that each HB has it's own rules about the playrooms and who may enter and who may not, depending on the rooms. I'm not going to go in details for each HB, you will get a tour as first timer when you go in for the first time.
I do recommend going with someone you're comfortable with, but it's not 100% necessary.